The impacts of Delphi communication structure on small and medium sized asynchronous virtual teams

The improvement of Internet technology has motivated distributed work groups to collaborate without meeting face to face. Although asynchronous meetings through Web-based group communications systems enable groups dispersed temporarily and geographically to collaborate more flexibly, parallel and non-linear communication among dispersed members also challenge effective and efficient group coordination. Moreover, the Web-based asynchronous meeting is distinguished not only from the face-to-face meeting but also from the synchronous computer-supported meeting in terms of coordination process. However, previous asynchronous group communications or virtual team research focused more on the comparison of this new type of meeting with the face-to-face meeting. Not many research efforts have been exerted to improve the productivity of this new form of meeting and find ways to overcome its disadvantages. Facilitation was proved effective to enhance the productivity of synchronous meetings. However the effect of structured discussion through facilitation was not clear in asynchronous meeting settings even though facilitation is a common practice in asynchronous group communication systems. This study examined the effect of a facilitated structure in improving the productivity of asynchronous decision-making groups. Delphi was chosen as the facilitated structure because it has been widely used as the paper-and-pencil-based structure to facilitate dispersed experts in collecting their opinions. In this study a computer-based Delphi structure was implemented through asynchronous Computer-Mediated Communication. A 2X2 controlled experiment was conducted to investigate the effect of Delphi structure on the effectiveness of small-sized (5-6 members) and medium-sized (10-12 members) asynchronous computer-supported groups. The formal facilitation using Delphi structure was effective to improve the productivity of asynchronous groups in generating more ideas. On the contrary, informal leadership by group coordinators seems to have played a more important role in producing better reports. In terms of per person ideas, small-sized groups were more productive, even though medium-sized groups produced more total ideas than small-sized groups. The superiority of Delphi groups and small-sized groups is related to their higher equality of participation. This result suggests that in asynchronous meetings, equal participation of group members in discussion is important in improving idea generation productivity while in synchronous meetings, the process loss of production blocking plays a crucial role

Immune-Checkpoint Inhibitors-Induced Type 1 Diabetes Mellitus: From Its Molecular Mechanisms to Clinical Practice

With the increasing use of immune-checkpoint inhibitors (ICIs), such as anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and anti-programmed cell death-1 (PD-1), for the treatment of malignancies, cases of ICI-induced type 1 diabetes mellitus (ICI-T1DM) have been reported globally. This review focuses on the features and pathogenesis of this disease. T1DM is an immune-related adverse event that occurs following the administration of anti-PD-1 or anti-programmed death ligand-1 (PD-L1) alone or in combination with anti-CTLA-4. More than half of the reported cases presented as abrupt-onset diabetic ketoacidosis. The primary mechanism of ICI-T1DM is T-cell stimulation, which results from the loss of interaction between PD-1 and PD-L1 in pancreatic islet. The similarities and differences between ICI-T1DM and classical T1DM may provide insights into this disease entity. ICI-T1DM is a rare but often life-threatening medical emergency that healthcare professionals and patients need to be aware of. Early detection of and screening for this disease is imperative. At present, the only known treatment for ICI-T1DM is insulin injection. Further research into the mechanisms and risk factors associated with ICI-T1DM development may contribute to a better understanding of this disease entity and the identification of possible preventive strategies

Comparison of quality of life and related factors according to premature menopause using the Korea National Health and Nutrition Examination Survey (2014–2017)

Purpose The purpose of this study was to compare the health‐related quality of life of premature menopausal women with that of normal postmenopausal women and to identify factors related to quality of life in these two groups. Methods A secondary analysis was conducted of a sample of 5,910 postmenopausal women drawn from women aged 19–79 years, using raw data from the Korea National Health and Nutrition Survey between 2014 and 2017. Quality of life was compared between premature menopausal women and normal postmenopausal women using the t‐test and chi‐square test, and factors related to quality of life were analyzed by multivariate logistic regression using SAS version 9.4. Results There was no significant difference in quality of life between premature menopausal women and normal postmenopausal women. Subjective health status and symptoms of depression were identified as factors related to quality of life in women with premature menopause, while engaging in aerobic physical activity, subjective health status, stress, and symptoms of depression were found to be related to quality of life among normal postmenopausal women. Conclusion It is necessary to support self‐care measures for both premature and normal menopausal women to adapt to changes caused by menopause, and multidimensional strategies should be developed considering postmenopausal women’s subjective health status and symptoms of depression to improve their quality of life

The Distribution Strategy Of A Representative Fair Trade Organization In Korea: The Case Of Beautiful Coffee

This case study analyzes the distribution strategy of Beautiful Coffee, a leading fair trade organization in Korea. Because of their focus on matters of public interest, fair trade organizations often face financial difficulties, and such difficulties can limit their growth and force them to pursue differentiated distribution strategies. The results indicate that Beautiful Coffee can serve as a good role model for fair trade organizations and have important practical implications for firms pursuing sustainable growth as a social enterprise

Ductographic Findings of Breast Cancer

Ductography has become the gold standard for the evaluation of patients exhibiting pathologic nipple discharges. In nine patients (age range, 29-67 years; median age, 51 years) with invasive (n=5) or intraductal (n=4) cancer, ductographic findings were recorded, then correlated with mammographic and sonographic findings. Common ductographic findings included complete ductal obstruction, multiple irregular filling defects in the nondilated peripheral ducts, ductal wall irregularities, periductal contrast extravasation, and ductal displacement. Faint microcalcifications or ill-defined masses, which were not opacified by contrast material, were often discovered adjacent to ductal abnormalities. Mammographically and sonographically occult diffusely spreading intraductal cancers often manifested as pathologic nipple discharge. In such cases, meticulous ductographic examinations and interpretations were crucial in order not to miss breast cancers

Micro-nano hybrid structures with manipulated wettability using a two-step silicon etching on a large area

Nanoscale surface manipulation technique to control the surface roughness and the wettability is a challenging field for performance enhancement in boiling heat transfer. In this study, micro-nano hybrid structures (MNHS) with hierarchical geometries that lead to maximizing of surface area, roughness, and wettability are developed for the boiling applications. MNHS structures consist of micropillars or microcavities along with nanowires having the length to diameter ratio of about 100:1. MNHS is fabricated by a two-step silicon etching process, which are dry etching for micropattern and electroless silicon wet etching for nanowire synthesis. The fabrication process is readily capable of producing MNHS covering a wafer-scale area. By controlling the removal of polymeric passivation layers deposited during silicon dry etching (Bosch process), we can control the geometries for the hierarchical structure with or without the thin hydrophobic barriers that affect surface wettability. MNHS without sidewalls exhibit superhydrophilic behavior with a contact angle under 10°, whereas those with sidewalls preserved by the passivation layer display more hydrophobic characteristics with a contact angle near 60°